International 500 Mile
Sweepstakes
Indianapolis Motor Speedway
2.5 Mile Brick Oval
200 Laps/500 Miles
May 30, 1921
| Finish | Start | Driver | Car # | Sponsor/Name | Chassis | Engine | Laps | Status |
Points |
| 1 | 20 | Tommy Milton | 2 | Frontenac | Frontenac | Frontenac | 200 | 5:34:44.65 89.621 | 1,000 |
| 2 | 2 | Roscoe Sarles | 6 | Duesenberg | Duesenberg | Duesenberg | 200 | 5:38:34.03 88.609 | 520 |
| 3 | 8 | Percy Ford | 23 | Fronteanc | Frontenac | Frontenac | 200 | 5:52:50.30 85.025 | 127 |
| 4 | 9 | Eddie Miller | 5 | Duesenberg | Duesenberg | Duesenberg | 200 | 5:54:24.98 84.646 | 65 |
| 5 | 13 | Ora Haibe | 16 | Sunbeam | Sunbeam | Sunbeam | 200 | 5:55:58.20 84.277 | 90 |
| 6 | 14 | Albert Guyot | 9 | Duesenberg | Duesenberg | Duesenberg | 200 | 6:01:17.70 83.035 | 30 |
| 7 | 10 | Ira Vail | 3 | Leach | Miller | Miller | 200 | 6:14:17.47 80.152 | 50 |
| 8 | 15 | Bennett Hill | 21 | Duesenberg | Duesenberg | Duesenberg | 200 | 6:19:06.74 79.132 | 32 |
| 9 | 21 | Ralph Mulford | 8 | Frontenac | Frontenac | Frontenac | 177 | Flagged | 35 |
| 10 | 17 | René Thomas | 15 | Sunbeam | Sunbeam | Sunbeam | 144 | Broken water hose | |
| 11 | 18 | Tom Alley | 27 | Frontenac | Frontenac | Frontenac | 133 | Broken connecting rod | |
| 12 | 1 | Ralph DePalma | 4 | Ballot | Ballot | Ballot | 112 | Broken connecting rod | |
| 13 | 4 | Eddie Hearne | 1 | Revere/Duesenberg | Duesenberg | Duesenberg | 111 | Broken oil line | |
| 14 | 19 | Jimmy Murphy | 24 | Duesenberg | Duesenberg | Duesenberg | 107 | Hit wall | |
| 15 | 16 | Riley Brett | 17 | Junior 8 | Brett | Brett | 91 | Hit wall | |
| 16 | 23 | Cornelius Van Ranst | 28 | Frontenac | Frontenac | Frontenac | 87 | Broken oil line | |
| 17 | 3 | Joe Boyer | 7 | Duesenberg | Duesenberg | Duesenberg | 74 | Broken rear axle | |
| 18 | 6 | Jean Chassagne | 19 | Peugeot | Peugeot | Peugeot | 65 | Lost engine hood | |
| 19 | 5 | Jules Ellingboe | 22 | Frontenac | Frontenac | Frontenac | 49 | Broken oil line | |
| 20 | 11 | André Boillot | 14 | Talbot-Darracq | Sunbeam | Sunbeam | 41 | Connecting rod bearing | |
| 21 | 7 | Louis Fountaine | 18 | Junior 8 | Brett | Brett | 33 | Wrecked, lost brake | |
| 22 | 22 | Joe Thomas | 25 | Duesenberg | Duesenberg | Duesenberg | 24 | Broken steering, wreck | |
| 23 | 12 | Howdy Wilcox | 10 | Peugeot | Peugeot | Peugeot | 22 | Broken connecting rod | |
| -- | -- | Joe Boyer | 9 | Duesenberg | Duesenberg | Duesenberg | 38 | Relieved Guyot | |
| -- | -- | Jules Ellingboe | 23 | Fronteanc | Frontenac | Frontenac | 95 | Relieved Ford | |
| -- | -- | Eddie Miller | 9 | Duesenberg | Duesenberg | Duesenberg | 61 | Relieved Guyot | |
| -- | -- | Jimmy Murphy | 5 | Duesenberg | Duesenberg | Duesenberg | 107 | Relieved E. Miller | |
| -- | -- | Andy Burt | 23 | Fronteanc | Frontenac | Frontenac | 11 | Relieved Ford | 15 |
| -- | -- | Eddie Pullen | 24 | Duesenberg | Duesenberg | Duesenberg | X | Relieved Murphy | |
| -- | -- | Harry Thicksten | 17 | Junior 8 | Brett | Brett | X | Relieved Brett | |
| -- | -- | Jerry Wonderlich | 21 | Duesenberg | Duesenberg | Duesenberg | 42 | Relieved B. Hill | 8 |
| -- | -- | Joe Boyer | 25 | Duesenberg | Duesenberg | Duesenberg | -- | Driven by J. Thomas | |
| -- | -- | Tommy Milton | X | Duhrn Duesenberg | Duesenberg | Duesenberg | -- | Withdrew | |
| -- | -- | Eddie Pullen | 25 | Duesenberg | Duesenberg | Duesenberg | -- | Driven by J. Thomas | |
| -- | -- | L. L. Corum | 27 | Frontenac | Frontenac | Frontenac | -- | Driven by Alley | |
| -- | -- | Mervin Headley | 26 | Frontenac | Frontenac | Frontenac | -- | Did not qualify | |
| -- | -- | Dario Resta | X | Sunbeam | Sunbeam | Sunbeam | -- | Did not arrive | |
| -- | -- | John Thiele | 21 | Duesenberg | Duesenberg | Duesenberg | -- | Driven by B. Hill |
Known riding mechanics in this race:
| Finish | Start | Driver | Mechanic | Car # | Sponsor/Name | Chassis | Engine | Laps | Status |
| 1 | 20 | Tommy Milton | Harry Franck | 2 | Frontenac | Frontenac | Frontenac | 200 | 5:34:44.65 89.621 |
| 2 | 2 | Roscoe Sarles | Ernie Ansterburg | 6 | Duesenberg | Duesenberg | Duesenberg | 200 | 5:38:34.03 88.609 |
| 3 | 8 | Percy Ford | Joseph Bonadeo | 23 | Frontenac | Frontenac | Frontenac | 200 | 5:52:50.30 85.025 |
| 4 | 9 | Eddie Miller | Lester Vick | 5 | Duesenberg | Duesenberg | Duesenberg | 200 | 5:54:24.98 84.646 |
| 5 | 13 | Ora Haibe | Floyd Kemp | 16 | Sunbeam | Sunbeam | Sunbeam | 200 | 5:55:58.20 84.277 |
| 6 | 14 | Albert Guyot | John Nelson | 9 | Duesenberg | Duesenberg | Duesenberg | 200 | 6:01:17.70 83.035 |
| 7 | 10 | Ira Vail | A. G. Kenyon | 3 | Leach | Miller | Miller | 200 | 6:14:17.47 80.152 |
| 8 | 15 | Bennett Hill | John Thiele | 21 | Duesenberg | Duesenberg | Duesenberg | 200 | 6:19:06.74 79.132 |
| 9 | 21 | Ralph Mulford | Thane Houser | 8 | Frontenac | Frontenac | Frontenac | 177 | Flagged |
| 10 | 17 | René Thomas | Albert Divo | 15 | Sunbeam | Sunbeam | Sunbeam | 144 | Broken water hose |
| 11 | 18 | Tom Alley | Marcel Treyvoux | 27 | Frontenac | Frontenac | Frontenac | 133 | Broken connecting rod |
| 12 | 1 | Ralph DePalma | Peter DePaolo | 4 | Ballot | Ballot | Ballot | 112 | Broken connecting rod |
| 13 | 4 | Eddie Hearne | Harry Hartz | 1 | Revere/Duesenberg | Duesenberg | Duesenberg | 111 | Broken oil line |
| 14 | 19 | Jimmy Murphy | Ernie Olsen | 24 | Duesenberg | Duesenberg | Duesenberg | 107 | Hit wall |
| 15 | 16 | Riley Brett | Herschell McKee | 17 | Junior 8 | Brett | Brett | 91 | Hit wall |
| 16 | 23 | Cornelius Van Ranst | Wally Butler | 28 | Frontenac | Frontenac | Frontenac | 87 | Broken oil line |
| 17 | 3 | Joe Boyer | Alfred Nielsen | 7 | Duesenberg | Duesenberg | Duesenberg | 74 | Broken rear axle |
| 18 | 6 | Jean Chassagne | Alex Jehel | 19 | Peugeot | Peugeot | Peugeot | 65 | Lost engine hood |
| 19 | 5 | Jules Ellingboe | Plemmy Woodruff | 22 | Frontenac | Frontenac | Frontenac | 49 | Broken oil line |
| 20 | 11 | André Boillot | Theodore Le Du | 14 | Talbot-Darracq | Sunbeam | Sunbeam | 41 | Connecting rod bearing |
| 21 | 7 | Louis Fountaine | Cotton Henning | 18 | Junior 8 | Brett | Brett | 33 | Wrecked, lost brakes |
| 22 | 22 | Joe Thomas | Ray Cariens | 25 | Duesenberg | Duesenberg | Duesenberg | 24 | Broken steering, wrecked |
| 23 | 12 | Howdy Wilcox | Russell Wright | 10 | Peugeot | Peugeot | Peugeot | 22 | Broken connecting rod |
| Lap Leaders | Total | Laps |
| Ralph DePalma | 108 | 1, 3-5, 7-110 |
| Tommy Milton | 90 | 111-200 |
| Joe Boyer | 1 | 2 |
| Roscoe Sarles | 1 | 6 |