| Driver | Nationality | Years Active |
| Wally Zale | USA | 1931, 33-34 |
| Eddie Zalucki | USA | 1946-49 |
| Alessandro Zampedri | ITA | 1994-97 |
Alex
Zanardi 
 |
ITA | 1996-98, 2001 |
| Gus Zarka | USA | 1935-37 |
| Bob Zauer | USA | 1933, 36 |
| Louis Zborowski | POL | 1923 |
| Len Zengel
|
USA | 1909, 11-12 |
| Jack Ziegler | USA | 1981 |
| Denny Zimmerman | USA | 1968-72, 74 |
| Eddie Zimmerman | USA | 1946 |
| George Zimmerman | USA | 1927-28 |
| Paul Zuccarelli | ITA | 1912-13 |
| Frank Zucker | USA | 1915 |
| Ben Zukor | USA | 1950 |
| Nicholas Zwick | USA | 1918-19 |
| Charles Zwolsman | NED | 2005-06 |